Tuesday, August 30, 2011

what do you want



Who’s in control of your actions? Are the decisions you make a reflection of what you truly want to do?

For the vast majority of us, it’s the influence of other people – friends, family, colleagues, role models etc. This is for the sole reason that we have been thought to operate in this manner from young. We were taught that feeling accepted was important, and that when we “listened to what others said”, we were good. Our education system taught us the importance of strength in numbers, not to want to be singled out from the crowd, and we learnt that so well that as adults, the sheep mentality followed us.  

There’s an adage that goes - 
“Most people are other people. Their thoughts are someone else’s opinions, their lives a mimicry, their passions a quotation.”  – Oscar Wilde
We are afraid of being called a “let down” just because we are different. We crave people’s approval and attention like a basic need. Most of us even live unhappily because we spend so much time living out our lives as if it were that of another person - we impoverish our own existence to get our own constant fix of approval.

All this, despite the fact that most of us also crave freedom, despite seeking the approval of others. In the end, it all boils down to one question – do you genuinely want to be carefree and pull your own strings, or do you want the approval of others.

If you choose to be approved by others, take note that in the end, everyone has their own agendas and mostly care only about themself more than they care about you. Therefore, before you go all out to please someone, weigh carefully whether this is to your benefit or to theirs. Because, if we try to live constantly the way others want us to live, we will constantly make consents which, may not be to the best of our own interests and personal development. And in the end, you do not want to wake up one day thinking – damn … I have not lived a life I wanted…

Credit By : http://enpap.blogspot.com

Lakme Fashion Show 2011










Credit By : http://enpap.blogspot.com

What Lay People Should Know about Cloning – Fear Fuelled Objections (opinion) [Part 1]

The pen is mightier than the sword.


First there was The Boys from Brazil – a 1976 novel by Ira Levin which imaged an evil uprising made possible through cloning technology. This intriguing scale of evil even made its way into the cinema in 1978.

The story depicts an amateur Nazi hunter, Barry Kohler and a professional Nazi hunter, Ezra Lieberman tracking down a case of assassinations by the Comrades’ Organisation, an international brotherhood of old Nazis. The evil plot includes a series of assassination in progress of 94 men around Europe, Canada and United States over a period of two and a half years. All the victims were 65-year-old civil servants with positions of minor bureaucratic authority, all to be killed on specific dates instructed by Josef Rudolf Mengele (an actual historical figure who was a German SS officer in the Nazi concentration camp Auschwitz-Birkenau, who was infamous for performing gruesome human experiments on camp inmates, including children, earning him the nickname Angel of Death).

Lieberman interviews three of the victims’ wives, one in Germany, another in the United States and the last in London and notices that all wives were much younger than their husbands and have teenage sons who looked identical to each other – black hair, blue eyes, pale skin and lanky body. Upon further investigation Lieberman discovers that all the three boys proved to be the result of illegal adoptions of infants from Brazil by the Comrades’ Organisation to couples all over Europe and North America who fits a description – government civil servants husbands and a wife twenty years younger.

The Angel of Death’s plot was to revive Nazi. But how are the illegal adoptions and assassinations going to do that? If you knew about Hitler’s background – that his father was a politically conservative civil servant, whom he was rebellious against due to the abusiveness and authoritarian parenting, and a mother twenty years younger than the father, and that his father died at the age of 65 when he was turning 14 – you probably would have guessed Mengele’s plot. If you didn’t know about Hitler’s background, then you would have guessed it just after reading the pervious sentence.

As indulging as the story may be, after placing the book down or walking out of the cinema, one would realise that for that moment of indulgence, it was far from reality.

Then there was In His Image: The Cloning of a Man – a 1978 non-fiction book written by a respected and credible science writer and a medical reporter for Time who even contributed articles to The New York Times, David Michael Rorvik, which reports his encounter with a wealthy unmarried man and without children, referred to as “Max”, in 1973 who was in search of a doctor to clone himself for a son with the offer of one million dollars. Rorvik agreed to assist him and found a doctor, referred to as “Darwin”. Darwin used the nuclear transfer technique similar to that used on frogs in the 60s, which proved successful on Max. The cloning was performed in a secret tropical Pacific island controlled by Max. The clone was born on December of 1976 by a surrogate mother referred to as “Sparrow”.

This book did not give the same reaction as The Boys from Brazil did once the book is placed down, as the events of this book were true. Even before its publication, the story made its way to the front page of the March 3rd 1978 publication of the New York Post announcing the first human cloning. Many believed the tale, and even his publisher was unsure. In His Image: The Cloning of a Man became a national best seller as a non-fiction title, which brought up the public’s fear on biotechnology and ethical issues towards cloning and genetic manipulation to the centre of attention.

Of course this claim is now known as a hoax, as if it were true the first human cloning would have preceded the first test tube baby – the first human in vitro fertilisation, a technology which clearly should precede and be inferior to human cloning. Rorvik and his publisher was sued for defamation by a scientist whose research was cited in the book, and was labelled “fraud and a hoax” by the court when Rorvick failed to provide concrete evidence. Rorvik’s motives for the fraud remain unclear. Some speculate that his motives were to raise awareness on the ethics of cloning.

These two books truly started the fire and stirred up the fear to question the ethics of cloning and especially human cloning, as the pen is mightier than the sword.

This fear was preceded by breakthroughs such as the deciphering of the genetic code in 1966, the isolation of DNA ligase (specific type of enzyme that repairs single-stranded discontinuities in double stranded DNA molecule) in 1967, the first isolation of gene in 1969, the isolation if restriction enzyme in 1970, the recombination of DNA molecules in 1972, and the first recombination of DNA organisms in 1973. Further more in 1980, the United States Supreme Court ruled that “live, human made microorganism is patentable material” after court battles between Anada M. Chakrabarty from G.E. and Sidney A. Diamond, the Commissioner of Patents and Trademarks when Chakrabarty developed a strain of oil eating microbes but was rejected a patent by the U.S Patent and Trademark Office in 1978. This ruling led to the birth of the modern biotech industry. Later the Human Genome Project (HGP) , a 13 year long international collaborative scientific research project primarily to identify all the approximately 20,000-25,000 genes in human DNA, and to determine the sequences of the 3 billion chemical base pairs that make up human DNA which began on October 1st 1990 and ended on April of 2003.

Creating Life? Playing God?


The “playing god” argument for cloning is heard of all over. Proponents of the argument view reproductive cloning as creating life, hence playing god and hence immoral and unethical. Firstly, in this context, what does it mean to create life? Isn’t making babies by having sex also creating life? Life is being created through conception, isn’t it?

If what is meant by creating life is to artificially conceive a baby, then artificial insemination (AI), in vitro fertilisation (IVF) and artificial embryonic splitting – in this case, one more extra life than what was naturally under development – too are processes of creating life. So would be the innocuous process of artificial pollination. But artificial pollination isn’t condemned as creating life.

But if what is meant by creating life is to create life out of non-life, then the statement is completely false, although this has actually already been achieved on May of 2010 by John Craig Venter – a work which costs 15 years of research and about 40 million USD to create the chromosomes that control each cell of the bacteria from scratch, eventually creating the first synthetic life form. But don’t worry! Religious groups have already fulfilled their responsibility in taking a stance to correctly condemn this creation of life, as they always do ever since the beginning of scientific advancement to many scientific researches and newly discovered scientific facts which their mythical based beliefs just so happen to contradict. In fact, going further back in time to 1952, the first Miller-Urey experiment was conducted, which involves using natural, non-life related chemical reactions to form amino acids, “the building blocks of life”.

As for AI and IVF, the process still requires the existing building blocks of a newborn – (the DNA from) a sperm, (the DNA from) an ovum and a female to give birth to the baby. Similarly cloning requires the intended DNA for the clone, an enucleated ovum and a female to give birth to the clone. With cloning, scientists have merely found ways into the existing phenomena in the system of life to artificially reproduce asexually.

So allow me to put it straight and clear: Cloning is not creating life anymore than artificial pollination is. If to clone is to create life, so is artificial pollination.

Aside from the laboratory procedures, how cloning differs from IVF and AI is the resulting DNA of the offspring. AI and IVF will produce offspring with the combined DNA of half that of the male sperm donor and half that of the impregnated female – 1: male and female biological parents, where the female biological parent gives birth to the offspring. IVF can also produce offspring with the combined DNA of half that of the male sperm donor and half that of the female ova donor and without the DNA of the female who would give birth to the offspring – 2: male and female biological parents and a surrogate mother. On the other hand, cloning can produce offspring with the DNA of a single donor (male or female) utilising a surrogate mother, or if the donor is a female fit for pregnancy, she can give birth to the offspring herself – 3: one female biological parent giving birth to her own offspring, and 4: one male or female biological parent and a surrogate mother. Looking at these four combinations of “biological-to-birth parents” artificial reproduction, we can see that combinations “3” and “4” are just the asexual version of “1” and “2”. Unless asexual reproduction as itself is unethical, I don’t see how anyone can accept the ethics AI and IVF without accepting the ethics of human cloning – assuming that the technology is safe, that is.

IVF today doesn’t seem to have that invisible hat with the word “immoral” written on it as much as it used to – it is no longer taboo. But before 25th July, 1978, the birth of the first test tube baby, Louise Brown, IVF is seen to be as immoral as cloning is seen now. People fear such medical procedures out of ignorance and that it is just a question of breaking the taboo, the argument is.


But the truth is that there still are religious objection against IVF and AI just as there are against condoms. Their argument for this, which they also use against cloning, is mostly based on the “this is how we are meant to conceive, and not like that” logic. Or in a broader manner “according to god, this is how it should be, and not like that” – the acclaimed divine fascism of a still-to-be-discovered conscious creator of the known world.

Another argument puts forth the idea of destroying our humanity. That clone children will not be treated as humans, but rather as products and objects. Once again, this is a reminiscence of the objection against the birth of Louise Brown 33 years ago. Since then, well over a million human babies have been born healthily from IVF and none of them are treated as products and objects. Some of your friends may very well be products of IVF. You won’t even be able to make out which of your friends are test tube babies and which aren’t unless you were told so.

Actually, there is no need to go so far as AI, IVF and artificial pollination to reveal the inconsistency in the argument – we could still stay within the topic of cloning to do that. Proponents of the “creating life” argument seem to not be too bothered about artificial vegetative propagation, which is a form of reproductive cloning, but for plants. Why isn’t the “creating life, hence playing god” logic used seriously to condemn horticulture? Some less serious proponents of the argument also don’t seem to be too bothered about animal cloning as well.

Now, allow me to put this part straight and clear: Cloning is not creating life anymore than artificial vegetative reproduction is, as this ancient process of artificial vegetative reproduction itself is cloning.

Honestly speaking, the basis of the whole “playing god” argument is pretty much groundless, in my opinion as there are various versions of gods from the various groups of people, all claiming that theirs are correct and the rest are wrong. On top of that, how is the sin of creating life going to practically affect our or anyone’s lives negatively or positively?

What has consistency and practicality on why it may be immoral to clone humans, but is taken less seriously on animals and entirely not seriously on plants is the “doing harm” logic, discussed in the next section to justify how and why cloning may or may not be unethical.

Continue to [Part 2 (of 2)]...
Credit By : http://enpap.blogspot.com

What Lay People Should Know about Cloning – Fear Fuelled Objections (opinion) [Part 2]

The “Doing Harm” Logic
Let’s forget about the “creating life, hence playing god” argument.


Shouldn’t morality be based on whether or not the act does harm onto others?

Whether it is direct harm or indirect, whether it is long term or short, whether it is physical, emotional or psychological, whether it is to just one person or an entire population, the basis of immoral or unethical behaviour should be based on how the act does harm to others. An act in the legal scale as animal cruelty, man slaughter and polluting the environment to something to the scale of relationship such as cheating on one’s partner and even in a conversational scale such as using foul words, being rude and calling each other names have its unethical and immoral acceptance in this principle. Of course there are exceptions such as harming the guilty in order to protect the innocent, or physically harming someone for the sake of his or her survival. Morality based solely on the preference of the majority, the higher authority, the feared, traditions and laws is undoubtedly unreasonable. Human sacrifice, slavery, the burying of baby girls, racism and hatred towards homosexuality are just some of the many past practices – some still present – resulted from unreasonable based systems of morality.

Let’s start off with therapeutic cloning. The process requires creating a genetic embryonic replica of somebody, then later killing it. For some, such an act sound immoral. Yes, the living human embryos created are fated to be killed, but they are not capable of experiencing pain and suffering anymore than the live grasses we step on everyday and once in a while violently slicing them off with rotating blades powered by fuelled engines, as both plants and embryos do not have nerve cells. Human embryos show signs of neural folds indicating the beginning of the development of neural tube formation 19 days after fertilisation, whereas embryos are killed as the stem cells are removed which is only extractable in the blastocyst stage, which is in the day 4 or 5 after fertilisation.


Grasses, trees and plants are living beings, but never do we hear objections on the ethics of the abuse and massacre of these creatures because they are not capable of suffering. Imagine there being an NGO with the objective to end plant cruelty. Silly isn’t it? An NGO with the objective to end the cruelty against balls of brainless and nerveless cells too would be just as silly. The ethical issues raised on chopping down too many trees has got nothing to do with the non-existing pain and suffering of plants, but rather how this would affect the environment hence affecting the daily lives and survival of the human population, whom are capable of experiencing suffering.

This is the basic idea behind why there are no objections behind reproductive cloning of plants, but there are against that of animals and human. The topic in question here is the success rate and how safe the cloning techniques are. Aside from concerns of the cruelty towards animals involved in the cloning process, opponents are also concerned about the food safeties resulting from farm animal clone products.

Then, there is the argument on the value of human life. Therapeutic cloning will serve medical purposes, but no human life should be killed out of his or her will for the benefit for another, which I completely agree with. But firstly, human embryos are not humans – they are embryos. Just as plant seeds are not plants – they are seeds. Cushing a single seed is not equivalent to cutting down a whole tree, just as grinding coffee beans is not equivalent to deforestation. Yes, seeds and embryos have the potential of becoming fully developed plants and humans, but they are not fully developed plants and humans. Same goes with each and every one of your sperms or ova. Even if to kill human embryos is to disrespecting the value of human life, it doesn’t seem to apply practically to our lives.

The inconsistency of the “human life value” argument can also be revealed when compared to IVF. The process includes the in vitro insemination of the mother’s ova retrieved via a minor surgical procedure, by sperms retrieved from the father normally by ejaculation. Then the embryos are either cultured if they are meant to be freshly transferred into the mother’s uterus two to six days after insemination, or frozen (embryo cryopreservation) if they are meant to be transferred much later where they are thawed before the transfer. But before the transfer, out of the culture, the embryos undergo selection via laboratory grading methods to optimise pregnancy rates. If killing embryo against its will is equal to killing a human again his or her will, are freezing embryos and selecting embryos to be transferred against their will equal to freezing humans and selecting which to live and which not to against their will?

Lastly, commonly more than one embryo are transferred into the mother depending on her age and health factors as well as number of embryos available while expecting only one embryo to develop into a foetus to finally be born as a healthy baby. This process obviously includes the expectation of some transferred embryos, and yet IVF raises only few ethical issues while therapeutic cloning is extremely controversial and is banned in many countries. And the funny thing is that some of these countries which bans therapeutic cloning legalises IVF as well as abortion.

I understand that there are many more and stronger arguments and rebuttals against the killing of embryos which address how we consider a human to be a person. But this would be presented for the real debates in the succeeding article.

For now, let’s just assume that the cloning techniques are safe and reliable. In what way does human cloning do harm to others? And if human cloning does harm, in what way does AI and IVF does any less harm than human cloning? Certainly doesn’t seem like it, but keep in mind that morality should not just be based on reasoning alone. Morality should be based on educated rational reasoning. Ignorant reasoning will result in bad moral understanding. So maybe I am being ignorant towards the possible negative outcome of human cloning. Allow me to look into the possibilities brought upon opponents of human cloning.

Some argue that cloning to produce children may complicate a family, especially in relationship issues. Just imagine a couple with a son who is a clone of the father, and a daughter who is a clone of the mother. The siblings would not have any genetic relation to each other, and as the son and daughter reach their 20s, perhaps, they will be a splitting image as when the parents met and fell in love. Will the siblings find attraction towards each other as their parents did at their age? Or even worst, how would a parent feel when he or she finds himself or herself looking at a splitting image of his or her lover at the age they met? One may ask “How will the family ever work out?”

Ian Wilmut himself points out a possible negative implication of human cloning. If a parent were to clone a figure such as Einstein, Mozart, Beethoven, or any other genius public figure as their child, pressure may be placed upon the child by the parents to meet their expectations. The truth is that these kinds of pressure by parents occur all the time even without cloning. This is not an unnatural occurrence. Even if this does occurs with clones, it is not a question of how the child was conceived but rather the attitude of the parents towards their child.

As of the case of a son being a splitting image of the father at the same age, or a daughter to mother, this too occurs naturally all the time, yet it is innocuous. Even if a close family friend notices the extreme resemblance between the clone child and the parent, the friend probably would never figure out the truth behind the strong resemblance unless the friend was told so or witnessed a DNA test between the two. The friend would probably think it is just another case strong resemblance.

50 cents and son

On top of that, there already are families where there are no genetic relation between siblings as well as between parents and children through adoption, families with children who are from a previous marriage or from previous mirages of both parents, and there are also polygamous families. With these odd and unnatural genetic relations in families already seeming innocuous, families with clones as children should not seem so out of place. Sons will be sons and daughters will be daughters to parents regardless of their genetics.

So that’s it! There’s nothing wrong with human cloning, right?

No. I’m afraid I’m not finished yet… There still are more to look at.

Negative Possibilities on the Human Population
Greater divergence of social classes may be in threat due to human cloning with the addition of genetic modification. A social class of the genetically modified and the non-modified social classes may exist, dividing further the upper class and the lower – the wealthy and the poor – those who can afford genetic modification and those who can’t. Such speculated society my cause all sorts of tension and problems as artistically portrayed in one of my favourite science fiction movies Gattaca (1997), which introduces a form of discrimination worst than racism they called genoism – the discrimination against one’s genes. Aside from that, some simply fear against the kinds of eerie mutants and freaks which may be amongst us just like those straight out of science fiction tales as a result.


But this concern for genetic engineered clones is primarily the fear of eugenics, in which the most infamous example is the Nazi Germany’s principle of racial hygiene to improve the Aryan race which involved the mass sterilising of over 40,000 and the massacre of 70,000 people labelled as Lebensunwertes Leben – the ‘life unworthy of life’ which included but not limited to criminals, degenerates, dissidents, feeble-minded, homosexuals, idles, the insane and the weak.

Another possible concern contrasting to genetic modification and eugenics is the decrease of gene diversity in the human population. In organisms which reproduce only asexually, the population will have no gene diversity. If all the individuals in a population are genetically identical, and a virus which the sets of genes do not have the immunity against plagues them, the entire population will be wiped off from existence. This is the advantage of sexual reproduction as it is the source of gene diversity. Survival is the very reason sexual reproduction evolved. If asexual reproduction starts taking over sexual reproduction in the human population, the consequence may be negative towards our survival.

One last point which I can raise on the ethics of artificial reproduction of humans as a whole is that it would perhaps be somewhat selfish and inconsiderate to the society to chose artificial reproduction over adopting those who are readily available and in need for adoption when reproduction through sexual intercourse fails. There are already almost 7 billion humans in this planet! Do we need more? With overpopulation, balance is in risk. There won’t be enough drinking water, food, and adequate sanitation for the entire population. The fact that we know the implications behind overpopulation, it would be arguably irresponsibly unethical or immoral to allow it happen or especially when the power to prevent it is in our hands, choosing artificial sexual reproduction over adoption would just worsen the situation. Unlike the “creating life” and the “value of human life” argument, this statement applies to our practical lives.

Once again, education moral reasoning comes into play – in broader terms, one could argue that if one knows of the negative implications of a situation at risk which may affect oneself, one’s loved ones, or one’s local or the global community, which one has the power or can take measures to prevent, it would be irresponsibly unethical to stand by and chooses not to prevent it. It would be even more irresponsibly unethical and immoral to knowingly take actions, intentionally or not, which could worsen the situation at risk. To intentionally choose to remain ignorant towards the actions which could worsen the situation as an excuse too would be an irresponsible act.

Actually, these last three farfetched negative possibilities of human cloning can be the artistic yet scientific and practical representation of playing god. But this is not a conclusion stating that human cloning is unethical and immoral or not. These are just the few practical points that can be put forth against human cloning.

Anyway, most of these aren’t the real debates discussed currently. The scientific debates mostly question the safety, success rate and reliability of the current cloning techniques. Is animal cloning animal cruelty? When does human life begin? What are the rebuttals towards “embryos are not people”? Is human cloning is to use humans as guinea pigs? Is human cloning banned, and has it been performed? This is where this article shall end and where the next article will begin.


Credit By : http://enpap.blogspot.com

First Impressions


"Hi Karin, I'll be held up at work tomorrow, guess you've got to head down for class yourself. So sorry about it."


My heart sank, class would have probably been a bore without Gail, but well, I guess if there was anytime to get back on my own 2 feet alone, this was the time. Although I had half the mind to give the class a miss, I decided to give it the good ole' try and go for it. 


After work, I got my usual pack and made my way down to class. As I had subconsciously wanted to give the class a miss, I had inadvertently taken my time on the packing, bathing and making my way down to class. Midway on the road, it hit me that I was going to be 20minutes late for my 1.5 hour class. I began to get jumpy and the only thought on my mind at that time would be to make it to class ASAP.


As I got down from the bus, I rushed to class with books and pack in hand. That was when I first met Kenneth. They say that the first impressions are formed within seconds of meeting someone, and his impression of me must have been a pretty bad one. As I ran towards the door down the familiar hallway, I ran into him and both our books dropped. 


"OMG can you not see someone infront of you!" I blurted out as I regained my balance and picked up my items. 


"Well, I'm sorry that you dropped your stuff, but I was standing still and you ran into me." Kenneth replied.


"Whatever, I'm busy now!". I was too embarrassed and moody to apologize or dispense basic manners, thinking back, I was being a total bit*h. 


I made it to class, 25minutes late but managed to get back my composure and concentrate on the lesson. The day passed uneventfully, so I thought...

Credit By : http://enpap.blogspot.com

Enpap Lover

 
Design by Free WordPress Themes | Bloggerized by Lasantha - Premium Blogger Themes | cheap international calls